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Elevated blood urea levels causes and management

What is blood urea and elevated blood urea levels causes and managements, most common causes of elevated blood urea levels in clinical practice.

Blood urea - is synthesized by Liver ( in urea cycle ) as a metabolism of Proteins.

Normal range of blood urea is - 7 - 21 mg.

Causes of elevated Blood urea levels -

Renal disorders
Acute kidney injury
High protein in take
Increased protein break down
Volume loss - Burns
Dehydration
Shock
Urinary tract obstruction - stones,prostatic enlargement,carcinoma bladder.
Myocardial infarction ( MI )
Congestive heart failure
Bleeding inside the gastrointestinal tract
Certain drugs.
Liver failure


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Symptoms of elevated blood urea levels -

Fatigue
Signs of dehydration - dry skin,sunken eye balls,dry tongue etc.
Hypotension - secondary to volume loss
Signs of renal failure - swelling of both lower limbs, puffiness of face and volume overload state
signs of heart failure - orthopnea, PND,pain abdomen ( right sided),swelling of limbs


Management of elevated blood urea levels -
Depending on the cause for elevated urea levels -
If secondary to volume loss - replace patient with IVF ( Intravenous fluids)
treat the cause for volume loss
If secondary to congestive heart failure - treat with diuretics,Beta blockers and ACE inhibitors.

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